Listar por autor "Rybak, Jeffrey M."
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An azole tolerant endosomal trafficking mutant of Candida albicans is susceptible to azole treatment in a mouse model of vaginal candidiasis.
Peters, Brian M.; Luna Tapia, Arturo; Tournu, Héléne; Rybak, Jeffrey M.; Rogers, David P.; Palmer, Glen E. (Estados Unidos Antimicrobial Agents and Chemotherapy, 2017., 2019-09-24)We recently reported that a Candida albicans endosomal trafficking mutant continues to grow after treatment with the azole antifungals. Herein, we report that the vps21Δ/Δ mutant does not have a survival advantage over ... -
Loss of C-5 sterol desaturase activity results in increased resistance to azole and echinocandin antifungals in a clinical isolate of Candida parapsilosis.
Rybak, Jeffrey M.; Luna Tapia, Arturo; Dickens, C. Michael; Parker, Josie E.; Caudle, Kelly E. (Estados Unidos : Antimicrobial Agents and Chemotherapy, 2017., 2019-09-24)Among emerging non-albicans Candida species, Candida parapsilosis is of particular concern as a cause of nosocomial bloodstream infections in neonatal and intensive care unit patients. While fluconazole and echinocandins ...